Product ID:NOLVADEX 10 MG TABLETS
MSDS Date:01/04/1988
FSC:6850
NIIN:00F008523
MSDS Number: BGYDT

Emergency Phone: (800) 327-8633

Info Phone: (302) 575-3000

Cage: 70657

Cage: 70657

TAMOXIFEN CITRATE

CAS: 54965-24-1

RTECS: KH2387000

NON-HAZARDOUS FOR INGREDIENTS

LD50 LC50 Mixture:ORAL LD50 RAT 2.5 G TAMOXIFEN CITRATE/KG
Routes of Entry: Inhalation:YES Skin:NO Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:INGESTION: REPEATED AMOUNTS IN EXCESS
OF 10 MG/DAY OF THE ACTIVE MATERIAL CAN HAVE ADVERSE CLINICAL
EFFECTS ON WOMEN OF CHILDBEARING AGE. EYE: SLIGHT IRRITATION. SKIN:
SLIGHT DRYNESS & ERYTHEMA. INHAL ATION: SYSTEMIC EFFECTS MAY OCCUR
FROM DUST.
Explanation of Carcinogenicity:NONE
Effects of Overexposure:INGESTION: HIGH DOSE LEVELS MAY CAUSE
INTERFERENCE W/MENSTRUAL CYCLE IN WOMEN, CHARACTERIZED BY HOT
FLSHES, NAUSEA/VOMITING, IRREGULAR VAGINAL BLEEDING. SKIN: SLIGHT
DRYNESS/ERYTHEMA, RASH. EYE: SLIGH T IRRITATION, CATARACTS MAY
DEVELOP. INHALATION: SYSTEMIC EFFECTS MAY OCCUR FROM DUST.
Medical Cond Aggravated by Exposure:IN SOME INSTANCES SKIN RASH &
CATARACTS MAY DEVELOP.

First Aid:IN ALL CASES GET MED ATT. SKIN: WASH MATERIAL OFF W/SOAP &
WATER. WASH CONTAMINATED CLOTHING & DECONTAMINATE FOOTWEAR BEFORE
REUSE. EYES: IMMEDIATELY FLUSH W/WATER FOR AT LEAST 15 MINUTES. IF
REDNESS ITCHING/BURNING SENSATION DEVELOPS HAVEEXAMINATION.
INGESTION: IRRIGATE MOUTH W/WATER. INHALATION: REMOVE VICTIM TO
FRESH AIR.

Extinguishing Media:WATER FOG, FOAM, CO2, DRY CHEMICAL, HALON 1211.
Fire Fighting Procedures:SELF-CONTAINED BREATHING APPARATUS W/FULL
FACEPIECE & PROTECTIVE CLOTHING.
Unusual Fire/Explosion Hazard:CAN FORM EXPLOSIVE DUST CLOUDS IN AIR.
SENSITIVE TO IGNITION/ELECTROSTATIC DISCHARGE, BOTH A DUST CLOUD &
IN THE FORM OFPOWDER LAYER. FLAMMABLE VAPORS/HEATING.

Spill Release Procedures:WEAR EYE & RESPIRATORY PROTECTION DURING
CLEANUP. MOISTEN SPILLAGE & RECOVER. NEVER SWEEP SPILLAGE IN DRY
STATE. WASH RESIDUE FROM SPILL AREA W/HOT WATER CONTAINING
DETERGENT & FLUSH TO SEWER SERVICED BY A WASTEWATER TREATMENT
FACILITY.

Handling and Storage Precautions:FOLLOW PROCEDURES SPECIFIED IN THE
NATIONAL FIRE PROTECTION ASSOCIATION CODES & STANDARDS FOR HANDLING
COMBUSTIBLE DUSTS. PREVENT EYE CONTACT.
Other Precautions:MAINTAIN GOOD HOUSEKEEPING TO AVOID DUST BUILDUP.
PROTECT TABLETS FROM HEAT & LIGHT.

Respiratory Protection:IF NEEDED, USE MSHA-NIOSH APPROVED RESPIRATOR
FOR TOXIC PARTICULATES W/TLV <0.05 MG/M3.
Ventilation:USE LOCAL EXHAUST TO KEEP EXPOSURES TO A MINIMUM.
Protective Gloves:IMPERVIOUS
Eye Protection:GOGGLES
Other Protective Equipment:APRON, EYEWASH STATION IN WORK AREA.
Work Hygienic Practices:IF PRODUCT IS HANDLED IN ACCORDANCE W/GOOD
INDUSTRIAL HYGIENE PRACTICE, WILL NOT PRESENT AN ACTUAL HAZARD IN
WORKPLACE.
Supplemental Safety and Health

pH:N/D
Solubility in Water:INSOLUBLE
Appearance and Odor:WHITE TABLETS
Percent Volatiles by Volume:NEG

Stability Indicator/Materials to Avoid:YES
Hazardous Decomposition Products:COMBUSTION PRODUCTS: CO2, CO, NITROGEN
OXIDES, & OTHER TOXIC VAPORS.

Waste Disposal Methods:NOT LISTED AS HAZARDOUS WASTE UNDER RCRA.
HOWEVER DISPOSAL IN HAZARDOUS WASTE FACILITY IS RECOMMENDED.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.